Key Findings & Performance Implications
Before we go deep, here's what you need to know — fast. This summary shows the core systems that are either powering your performance or silently limiting it.
Watch Items
- DHEA declining (131 → 110)
- Hematocrit still elevated (56.4%)
- BUN/Creatinine ratio high (25)
Major Wins
- Insulin crossed into optimal (5.2 → 4.1)
- Glucose improved (104 → 94)
- Estradiol recovered (16.4 → 38.5)
- Thyroid normalized (T4: 2.8 → 5.0)
- IGF-1 trending up (140 → 166)
- PSA dropped 58% (7.2 → 3.0)
- CRP at 1.0 (controlled)
Your Performance Verdict
| System | Verdict | Status |
|---|---|---|
| Metabolic Efficiency | Optimized | Insulin 4.1 (<5 optimal). Glucose 94. HOMA-IR 0.95 (insulin sensitive). Foundation is solid. |
| Hormonal Balance | Dialed In | Testosterone stable, estradiol recovered (38.5), thyroid normalized. Protocol changes worked perfectly. |
| Recovery Capacity | Good | IGF-1 rising (140 → 166). Peptides working. Target 200-300+ for optimal recovery. |
| Inflammation Control | Excellent | CRP at 1.0 (optimal). PSA dropped from 7.2 to 3.0. Retatrutide effective. |
| Blood Viscosity | Improving | Hematocrit down from 58.3% to 56.4%. Right direction. Target 52-54%. |
What Changed Since Last Draw
Between your February and March draws, we made significant protocol adjustments. Here's what changed and how your body responded:
| Change | Result |
|---|---|
| Testosterone: 0.4cc 2x/week → 0.1cc daily | Hematocrit down (58.3% → 56.4%), RBC down (6.24 → 6.03) |
| Stopped topical testosterone cream | Additional reduction in total testosterone load |
| Thyroid: 1 grain + 25mcg T3 → 2 grains | T4 normalized (2.8 → 5.0), Free T4 Index doubled (0.7 → 1.5) |
| Stopped anastrozole (estrogen blocker) | Estradiol recovered to optimal (16.4 → 38.5 pg/mL) |
| Added Retatrutide peptide | PSA down 58% (7.2 → 3.0), CRP stable at 1.0 |
| Continued NAD + CJC-1295 + Ipamorelin | IGF-1 up (140 → 166), recovery improving |
| Dietary adjustments (reduced carbs, post-meal walks) | Glucose down (104 → 94), Insulin down (5.2 → 4.1) |
Key Takeaway: Your body responded quickly to protocol adjustments. This is exactly why we test monthly when optimizing.
Detailed Biomarker Analysis
CBC — Complete Blood Count
Oxygen Delivery & Fatigue Resistance
| Test | Your Result | Previous | Optimal Range |
|---|---|---|---|
| Hematocrit | 56.4% | 58.3% | 45-54% (TRT) |
| Red Blood Cells | 6.03 | 6.24 | 4.14-5.8 |
| Hemoglobin | 18.3 | 18.9 | 13.0-17.7 |
| Platelets | 173 | 147 | 150-450 |
What we see in your analysis:
- Improving. Hematocrit dropped 1.9 points — right direction. Daily TRT protocol is working.
- At 56.4%, you're still slightly elevated but trending down. Target 52-54% on next draw.
- Platelets recovered from 147 to 173 — as hematocrit comes down, platelets normalize.
- No blood donation needed yet. Retest in 4-6 weeks to confirm trend continues.
Performance Impact: Hematocrit measures the percentage of red blood cells in your blood. While low levels reduce oxygen-carrying capacity (lower VO₂, poor endurance, early fatigue), levels that are too high can thicken blood and impair circulation. Your current level (56.4%) is trending in the right direction — optimal hematocrit at the high end of normal (52-54%) maximizes oxygen delivery without blood viscosity issues.
Comprehensive Metabolic Panel
Energy Production, Recovery, Metabolic Stress
| Test | Your Result | Previous | Optimal Range |
|---|---|---|---|
| Glucose (Fasting) | 94 | 104 | 40-75 |
| Insulin (Fasting) | 4.1 | 5.2 | <5 |
| HOMA-IR | 0.95 | 1.33 | <1.0 |
| BUN | 29 | 26 | 6-24 |
| BUN/Creatinine Ratio | 25 | 19 | 9-20 |
What we see in your analysis:
- MAJOR WIN: Insulin crossed into optimal range (<5). This is the master switch for metabolic health.
- Glucose improving (104 → 94) confirms dietary changes are working.
- HOMA-IR 0.95 = you're insulin sensitive. Foundation is solid.
- BUN and BUN/Creatinine ratio elevated — likely dehydration. Target 100oz water daily.
Performance Impact: Fasting insulin controls metabolic flexibility and fat utilization. When insulin is high, your body struggles to access fat stores during long rides, leading to energy crashes, increased bonking risk, and poor endurance. Your insulin at 4.1 means you can now efficiently tap into fat for fuel during aerobic efforts — this is the foundation for sustained endurance performance. Glucose at 94 shows improved blood sugar control, supporting steady mid-ride power without the crashes.
What's Working — Celebrate The Wins
You made massive progress in one month. Here's what's dialed in:
Insulin 4.1 — Crossed into optimal (<5)
Glucose 94 — Down from 104
HOMA-IR 0.95 — Insulin sensitive
Estradiol 38.5 — Perfect for TRT
Thyroid normalized — T4 doubled
IGF-1 trending up — 140 → 166
PSA dropped 58% — 7.2 → 3.0
CRP at 1.0 — Optimal control
Your 3-Step Action Plan
1
Continue What's Working
Your protocol changes are working. Keep going with daily TRT injections, 2 grains thyroid, dietary changes (low carb after 7pm, post-meal walks).
2
Optimize Recovery & DHEA
Primary Focus: DHEA declining (131 → 110)
- Increase DHEA to 50mg daily — Target 250-350+
- Continue CJC-1295 + Ipamorelin — Push IGF-1 to 200-300+
- Continue Retatrutide — Get PSA below 2.0
3
Hydration & Kidney Support
Actions:
- Hydrate aggressively — Minimum 100oz water daily
- BUN 29 and BUN/Creatinine ratio 25 suggest dehydration
- Target ratio 9-20 within 4-6 weeks
Peptide Optimization Protocol
CJC-1295 + Ipamorelin Active
Goal: Increase IGF-1 from 166 to 200-300+ range
Dosing: CJC-1295 500 mcg + Ipamorelin 100 mcg before bed (DAILY)
Expected Results: IGF-1 rise of 30-50+ points within 4-6 weeks
Retatrutide Active
Goal: PSA trending down (3.0 → <2.0), CRP stable at 1.0
Dosing: 3 mcg every 5 days subcutaneous injection
Ready to Order Peptides?
Contact MC Nutrition for pharmaceutical-grade peptides and personalized dosing guidance.
Retest Schedule
4-6 Weeks (Late April 2026)
Critical Tests:
- CBC (hematocrit, RBC, platelets) — Goal: Hematocrit <54%
- Hormones (testosterone, estradiol, DHEA, IGF-1) — Goal: DHEA 150+, IGF-1 200+
- Metabolic panel (insulin, glucose, BUN, creatinine) — Goal: BUN/Creat ratio 9-20
- Inflammation (CRP, PSA) — Goal: CRP <1.0, PSA <2.0
Testing Frequency:
Monthly while optimizing (currently optimizing DHEA, IGF-1, hematocrit)
Every 3 months once stable (when all markers in optimal ranges)